Start • Knowledge Pathway • Staining Staining The staining process highlights tissue morphology, cell types, and structure to enable accurate tumor classification and diagnosis. View resources on how staining is practiced today, and how it may evolve in the future. Image Technical Brief of Heat Induced Epitope Retrieval Russell Myers, Ph.D. The value or power of IHC frequently is compromised by tissue fixation and processing. Learn More Image Introduction to Immunofluorescence James Burchette, HT (ASCP) A review of fluorochromes and the specialized microscope used in immunofluorescence techniques will begin this presentation. A typical (human skin and kidney) clinical specimen will be followed from receipt in the laboratory, through freezing, cryomicrotomy... Watch the webinar Image The Impact of Decalcification on Staining Loralee McMahon, MS HTL (ASCP) Different types of cancers frequently metastase to bone tissue. Treatment planning decisions are often based upon histology and special staining of these distant sites of disease. These decisions may rely on the outcome of immunohistochemistry, in situ... Watch the webinar Image Factor XIIIa Expression in Normal and Pathological Skin Guy Orchard, Ph.D. Catherine Stefanato, Ph.D. Learn More Image Techniques to Minimize Articular Cartilage Folding Sarah A. Mack After a joint has been decalcified, the loss of proteoglycans in the articular cartilage causes it to fold and ripple during the staining process. When this occurs, it makes it impossible to perform histo-morphometry or measurements of the cartilage. Learn More Image Basic Molecular Pathology and Pre-Analytical Variables Cecilia Yeung, Pathologist – Seattle Cancer Care Alliance, Assistant Professor – University of Washington, Dept. of Pathology In this session, we will briefly review the basics of molecular biology, examine critical factors which affect the quality of nucleic acids in the tissues and cells which are submitted for downstream molecular diagnostics, and briefly introduce some... Watch the webinar Image Understanding How Clinical HPV Testing Leads to Personalized Medicine At Its Best Human papillomaviruses (HPVs) are the etiologic agents for a significant fraction of many cancers in humans. Our understanding of the pathogenesis of these tumors has led to almost continuous refinement in our approach to managing patients at risk for these... Watch the webinar Image Single Cells Shine New Light on Lung Biology and Disease Keith Wharton, MD PhD FCAP In this webinar, Dr. Keith Wharton reviews a set of published studies using single cell analysis of lung tissues that have provided ground breaking insight into lung development and disease. Watch the webinar Image Staining ‘Other’ Specimen Loralee McMahon, MS HTL (ASCP) In surgical pathology more than ever, the laboratories are expected to do more with less. Taking on more specimens with less technical staff, or getting more stains out of tiny biopsies or fine needle aspirations have become the norm. The College of American... Watch the webinar Current page 1 Page 2 Page 3 Page 4 Page 5