Image HistoCore NANOCUT R - Discover New Breakthroughs Image HistoCore NANOCUT R - Discover New Breakthroughs Image Image Image X HistoCore NANOCUT R - Automated Research & Special Applications Rotary Microtome 14052458261 Discover New Breakthroughs with an Enhanced Level of Precision and Versatility When your microtomy involves diverse samples in order to discover new breakthroughs in your research projects, then NANOCUT R is the optimal solution for you. The new generation of microtomes from Leica Biosystems is built upon our 145+ year heritage of market-leading microtome design. From biomedical research to industrial applications, NANOCUT R can cut virtually anything you put in front of it. Cut sections that can be prepared for analysis in light microscopy and electron microscopy - down to 250nm (0.25µm, semi-thin). Preserve sample integrity when performing semi-thin sectioning with the Special Spindle and expanded Slow Speed Adjustment. Precisely stop the sample in the object head’s optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs.* Contact us to get a quote. Call +44 800 011 9620 to speak with a representative. *Source for Featured 3D Reconstruction Content: IGBMC, PHENOMIN, iCS Features Specifications Compare Downloads Resources Configurations Parts/Accessories Publications Product Features Precise and Consistent Semi-Thin Sectioning Avoid destruction of samples with the Special Spindle and expanded Slow Speed Adjustment capabilities which allow you to produce consistent semi-thin sections down to 250nm. Image Tackle the Toughest Materials with a Wide Range of Accessories Leverage a wide range of accessories available to the NANOCUT R, including holders for disposable steel and tungsten carbide blades, reusable knives, and a special holder for glass and diamond knives. Image 3D Reconstruction Stacking Technique Precisely stop the sample in the object head's optimal position for photo-capture of the cut sample surface when running 3-dimensional reconstruction programs. Image Precision-Orientation System Always get back to a 0-position home on the microtome, regardless of how you (or another tech) have changed the instrument's orientation. Image Force Balance System Minimize the risk of injury to the operator or specimen by an unbalanced object head. Product Specifications GENERAL Type: Motorized Nominal Supply Voltage: 100 / 120 / 230 / 240 V AC Nominal Frequency: 50/60 Hz Maximum Power Consumption: 100 VA Protection Class: I Power Fuses: 2 x T3,15 AL, 250V Pollution Degree: 2 Overvoltage Category: II Maximum Heat Emission: 340 J/s Operating Temperature Range: +18°C to +30°C Temperature Range During Storage: +5°C to +50°C Relative Humidity During Operation: 20% to Max. 80% Non-Condensing Relative Humidity During Storage: 10% to Max. 85% Non-Condensing DIMENSIONS & WEIGHT BASIC INSTRUMENT Width (including handwheel): 415 mm Depth (including waste tray): 620 mm Height (without top tray): 295 mm Weight (without accessories): Approx. 40 kg CONTROL PANEL Type: Separate control panel & in-housing integrated instrument control panel Width: 119 mm Depth: 193 mm Height: 50 mm Height (in inclined position): 81 mm Weight (net): 0.6 kg MICROTOME PERFORMANCE SPECS Specimen Feed: approx. 24 mm ±1 mm Vertical Stroke: 70 mm ±1 mm Large Standard Clamp: 55 x 50 x 30 mm Super Cassette Clamp: 68 x 48 x 15 mm Motorized Sectioning Speeds: 0 - 195 mm/s ±10% SPECIMEN RETRACTION In Manual Sectioning Mode: 5 - 50 µm (in 5 µm increments); can be turned off In Motorized Sectioning Mode: Speed-Dependent; can be turned off SPECIMEN ORIENTATION Horizontal: ± 8° Vertical: ± 8° SECTION THICKNESS SETTINGS Range: 0.25 - 50 µm Setting Values: 0.25 - 0.5 µm (in 0.25 µm increments) 0.5 - 5 µm (in 0.5 µm increments) 5 - 20 µm (in 1 µm increments) 20 - 50 µm (in 5 µm increments) TRIMMING SECTION THICKNESS SETTINGS: Range: 1 - 300 µm Setting Values: 1 - 10 µm (in 1 µm increments) 10 - 20 µm (in 2 µm increments) 20 - 50 µm (in 5 µm increments) 50 - 100 µm (in 10 µm increments) 100 - 300 µm (in 50 µm increments) ADDITIONAL SPECIFICATIONS Handwheel Balance System: Handwheel Lock / Brake: 2 Mechanical Locks, 1 Electronic Brake Safety Hand Wheel: Handle can be Centered WASTE TRAY Type Standard Waste Tray Waste Tray Volume 1400 ml SELECTABLE CUTTING MODES Rock Mode: - with activated retraction Single Mode: Continuous Mode: Step Mode: Program Mode: BLADE HOLDER Type: Semi-Thin Sectioning - Knife Holder GD Resin Sectioning - Knife Holder NZ or Knife Holder E-TC Paraffin Sectioning: 2-in-1 Blade Holder E North-South Movement: ± 24 mm East-West Movement: 3 Positions Lateral Displacement Function: via knife holder CE clamping top SPECIAL FEATURES Remaining Feed Indicator Visual and Acoustical Section Counter Section Thickness Totalizer Memory Position Special Spindle for Precise Semi-Thin Sectioning Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning Precise 3D Object Head Stop Position Quick Compare Chart Image HistoCore BIOCUT R Image HistoCore MULTICUT R Image HistoCore AUTOCUT R Image HistoCore NANOCUT R Product Image HistoCore BIOCUT R View product Image HistoCore MULTICUT R View product Image HistoCore AUTOCUT R View product Image HistoCore NANOCUT R Currently viewing Type Mechanical Semi-Motorized Motorized Motorized Precision-Orientation System Force Balance System 2-in-1 Blade Holder Specimen Cooling Option with RM CoolClamp Standard Waste Tray Silent Retraction Personalized Coarse Feed Wheel Fast Homing Memory Position Electronic Brake Special Spindle for Precise Semi-Thin Sectioning Expanded Slow Speed Adjustment for Precise Semi-Thin Sectioning Precise 3D Object Head Stop Position Downloads Configuration Guide Brochure - HistoCore Research Microtomes Configuration Guide - ZH (190671 ZH Rev A) Size: 2.01 MB, Type: pdf Brochure - HistoCore Research Microtomes Configuration Guide - DE (190671 DE Rev A) Size: 2.19 MB, Type: pdf Brochure - HistoCore Research Microtomes Configuration Guide - EN (190671 Rev A) Size: 1.23 MB, Type: pdf Brochure - HistoCore Research Microtomes Configuration Guide - ES (190671 ES Rev A) Size: 2.19 MB, Type: pdf Brochure - HistoCore Research Microtomes Configuration Guide - FR (190671 FR Rev A) Size: 2.19 MB, Type: pdf Brochure - HistoCore Research Microtomes Configuration Guide - IT (190671 IT Rev A) Size: 2.19 MB, Type: pdf Brochure - HistoCore Research Microtomes Configuration Guide - JP (190671 JP Rev A) Size: 1.19 MB, Type: pdf Brochure - HistoCore Research Microtomes Configuration Guide - KO (190671 KO Rev A) Size: 5.43 MB, Type: pdf Brochure - HistoCore Research Microtomes Configuration Guide - PT (190671 PT Rev A) Size: 2.18 MB, Type: pdf Brochure Brochure - HistoCore Research Microtomes Portfolio - DE (190367 DE Rev A) Size: 1.27 MB, Type: pdf Brochure - HistoCore Research Microtomes Portfolio - EN (190367 Rev A) Size: 2.81 MB, Type: pdf Brochure - HistoCore Research Microtomes Portfolio - ES (190367 ES Rev A) Size: 1.27 MB, Type: pdf Brochure - HistoCore Research Microtomes Portfolio - FR (190367 FR Rev A) Size: 1.27 MB, Type: pdf Brochure - HistoCore Research Microtomes Portfolio - IT (190367 IT Rev A) Size: 1.27 MB, Type: pdf Brochure - HistoCore Research Microtomes Portfolio - JP (190367 JP Rev A) Size: 734.58 KB, Type: pdf Brochure - HistoCore Research Microtomes Portfolio - KO (190367 KO Rev A) Size: 1.43 MB, Type: pdf Brochure - HistoCore Research Microtomes Portfolio - PT (190367 PT Rev A) Size: 1.27 MB, Type: pdf Brochure - HistoCore Research Microtomes Portfolio - ZH (190367 ZH Rev A) Size: 1.19 MB, Type: pdf IFU HistoCore NANOCUT R IFU 1v6I de Size: 3.7 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I en Size: 4.04 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I es Size: 3.69 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I fr Size: 3.73 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I hu Size: 3.69 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I it Size: 3.7 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I ja Size: 4.5 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I ko Size: 4.09 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I no Size: 3.65 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I pl Size: 3.7 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I pt Size: 3.69 MB, Type: pdf HistoCore NANOCUT R IFU 1v5J zh Size: 4.49 MB, Type: pdf HistoCore NANOCUT R IFU 1v6I sv Size: 4.06 MB, Type: pdf Case Studies & White Papers White Paper - High-Resolution Episcopic Microscopy using the HistoCore NANOCUT R - EN (18700 Rev A) Size: 1.14 MB, Type: pdf Certificate EU Declaration HistoCore NANOCUT R B en Size: 973.27 KB, Type: pdf Resources Product Feature Demo Videos X Force Balance System X Electronic Brake X Nanocut R instrument Frequently Asked Questions HistoCore Microtomes Does the new HistoCore RM antistatic tray fit on the older RM22xx series? No – the microtome base plates of both series have different dimensions and are not compatible with each other. How does the new antistatic waste tray reduce contamination? The antistatic waste tray is made from resistant antistatic material to avoid debris sticking to the walls of the tray. Is the new 2-in-1 blade holder compatible as a whole assembly with the older RM22xx series? Yes – only in the combination blade holder and 2-in-1 blade holder. Can we still use the backlighting with the new blade holder base for the 2-in-1 blade holder? No – the 2-in-1 blade holder base does not have the cut-out for the backlighting. Which accessories of the older RM22xx Series cannot be used with the HistoCore RMs anymore? Small section waste tray Large section waste tray Top tray – HistoCore RM top tray is 40% larger than the RM22xx series tray Cooling Device – too small to be placed on instrument top. However, it’s still good to place next to the instrument What is the advantage of the personalized coarse feed wheel? Convenience and ease-of-user – users can select their personal preference of coarse feed wheel turn direction. This feature is preserved from the RM22xx series, allowing users to trim at the high pace. What is the advantage of “Fast homing”? The return speed of the object head from front to home position has been reduced from 26 seconds (older series) to 13 seconds (new series). This accelerated speed helps to shorten the sectioning process each time the object head is returned to home position. What is the advantage of the Memory Position? When batch trimming and using the same height of blocks, Memory Position will help to accelerate the sectioning. First insert a new block Bring the block to the blade Set the Memo position (stored) Trim Remove block for re-cooling Press “Memo” – the object head returns to the set object change position Insert a new block – check position Trim again Configurations Basic Instrument (14052458261) Rotary microtome with Automated and Manual Modes Automatic Electronic Brake Special Spindle and expanded slow speed adjustment capabilities allows accurate specimen feeding for semi-thin sections of 250 nm Precise 3D object head stop position allows for taking pictures of the cut specimen surface after each section to enable 3D reconstruction Includes standard waste tray and top tray HistoCore NANOCUT R Parts/Accessories View all HistoCore NANOCUT R Parts/Accessories HistoCore NANOCUT R Publications View all HistoCore NANOCUT R Publications Education Training Resources (Knowledge Pathway)Introduction to Microtomy: Preparing & Sectioning Paraffin Embedded Tissue How to Guides4 Tips for Buying a Microtome
