ホーム • ライフサイエンス向けソリューション • 教育資料 • Peer-Reviewed Publications Repository - BOND RXm Peer-Reviewed Publications Repository - BOND RXm Image Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression Publication Year: 2022 Country: USA PMID: PMC8955233 Publication: Viruses. 2022;14(3):535. doi:10.3390/v14030535 Institute: Louisiana Animal Disease Diagnostic Laboratory (LADDL), Louisiana State University, Baton Rouge, LA 61329 Instrument: BOND RXm Authors: Carossino M, Kenney D, O’Connell AK, et al. Study Goals: To analyse neuroinvasion and neurodissemination in humans call into question the translational relevance of this model. Keywords: BOND RXm, translational animal model; comparative pathology; immunohistochemistry; in situ hybridization; viral pathogenesis; transmission electron microscopy; in vivo imaging Image Intranasal type I interferon treatment is beneficial only when administered before clinical signs onset in the SARS-CoV-2 hamster model Publication Year: 2021 Country: France PMID: PMC8376007 Publication: PLOS Pathogens. 2021;17(8):e1009427. doi:10.1371/journal.ppat.1009427 Institute: Ecole nationale vétérinaire de Toulouse, ENVT, INRAE, UMR 1225, IHAP, Université de Toulouse, Toulouse Instrument: BOND RXm Authors: Bessière P, Wasniewski M, Picard-Meyer E, et al. Study Goals: To investigate whether early type I IFN treatment is beneficial, while late interventions are ineffective, although not associated with signs of enhanced disease. Keywords: BOND RXm Image Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling Publication Year: 2021 Country: USA PMID: PMC7930198 Publication: Nature Communications. 2021;12(1). doi:10.1038/s41467-021-21615-4 Institute: Fred Hutchinson Cancer Research Center, Seattle, WA Instrument: BOND RXm Authors: Brady L, Kriner M, Coleman I, et al. Study Goals: To demonstrate the utility of digital spatial profiling for accurately classifying tumor phenotype, assessing tumor heterogeneity, and identifying aspects of tumor biology involving the immunological composition of metastases. Keywords: BOND RXm, metastatic prostate cancer, tumor heterogeneity, tumor phenotype, digital spatial profiling (DSP), multiplex Image Immunohistochemical Characterization of a Duodenal Adenocarcinoma with Pulmonary, Hepatic and Parapatellar Metastases in a Common Marmoset (Callithrix jacchus) Publication Year: 2021 Country: USA PMID: N/A Publication: Journal of Comparative Pathology Institute: Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, Maryland Instrument: BOND RXm Authors: Peterson C, Plunkard J, Johanson A, Izzi J, Gabrielson K. Study Goals: To investigate proximal duodenal adenocarcinoma with extensive metastatic disease in a common marmoset Keywords: BOND RXm, common marmoset; duodenal mucinous adenocarcinoma; metastases; pancytokeratin For Research Use Only. Not for use in diagnostic procedures. The content, including webinars, training presentations and related materials is intended to provide general information regarding particular subjects of interest to health care professionals and is not intended to be, and should not be construed as, medical, regulatory or legal advice. The views and opinions expressed in any third-party content reflect the personal views and opinions of the speaker(s)/author(s) and do not necessarily represent or reflect the views or opinions of Leica Biosystems, its employees or agents. Any links contained in the content which provides access to third party resources or content is provided for convenience only. For the use of any product, the applicable product documentation, including information guides, inserts and operation manuals should be consulted. Copyright © 2024 Leica Biosystems division of Leica Microsystems, Inc. and its Leica Biosystems affiliates. All rights reserved. LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH.