CytoInsight GSL Image Analysis & Case Management Solution for Cytogenomics

Flexible Image Analysis Platform for Every Cytogenomics Laboratory

The CytoInsight GSL automated image analysis and case management system is a comprehensive Cytogenomics solution that improves quality and turnaround time from acquisition to analysis while reducing hands-on time at every step in your process.

The CytoInsight GSL system improves image processing, provides system flexibility, and offers increased cybersecurity to deliver the tools to build your system to fit your Cytogenomics lab workflow.

From prepared slide to report and back, the CytoInsight GSL flexible platform for brightfield and fluorescence image analysis provides unlimited scanning for a walk-away solution to meet the evolving needs of your Cytogenomics laboratory.

For Research Use Only. Not for use in diagnostic procedures.

Product Features

The CytoInsight GSL system automates the time-consuming steps so the technologist can concentrate on analysis while improving time to results.

The CytoInsight GSL platform enables expansion with a fully automated scanning system, capture stations, and review stations.
Mixed batch scanning for combined scanning session of karyotyping, interphase spot scoring for FISH, and tissue FISH samples.
Unlimited scan capacity with hot swapping feature. Enables the user to pause the current batch and swap individual slide trays. Continuous scanning without the need for additional slide trays or towers.
Flexible configurations with increasing levels of automation available to best save technical resources for tasks requiring their invaluable expertise.

CytoInsight GSL provides the features and flexibility every Cytogenomics laboratory needs

CytoInsight GSL is an image analysis and case management system that provides Cytogenomics laboratories with an integrated, yet flexible platform for brightfield and fluorescence microscopy.

Configurations to match applications, throughput, and networking requirements.
Custom settings that can be quickly created by the user for any break-apart, enumeration, and fusion assays.

On-screen analysis improves ergonomics and gets techs out of the darkroom

Scanning, Capture, Analysis, and Reporting Modules for Brightfield and FISH

Karyotyping
Automated/manual spot counting for cellular FISH
Tissue FISH
Flexible karyotyping (non-human species)
Karyotype CGH
M-FISH
Multi-session scoring
Integrated, flexible reporting
Remote access

Experience high-resolution image quality with improved efficiency and flexibility

The CytoInsight GSL image analysis and case management system provides quality and flexibility with expertise in image analysis, robotics, optics, and microscopy featuring mixed batch scanning for continuous, combined sessions of karyotyping, interphase spot scoring for FISH, and tissue FISH.

12 megapixel CMOS camera for high-resolution images and rapid image processing
Robust, high-speed data transfer with solid state drive (SSD)
Flexible, intelligent automation with the motorized Leica DM6 B microscope

Reduce time to results and improve the consistency of your Cytogenomic analysis

Select the best captured cells, count, and analyze.

Analysis of cells are automatically tracked
Digital record of count and results
Track progress during analysis as each class is completed
Provides case statistics to enable the lab manager to optimize workload and quickly assess and react to productivity and quality changes
Image export functionality for use with automated karyotyping
Chromosome counting and numbering, identification of centromeres, segmentation, and classification of chromosomes into the karyogram

CytoInsight GSL Software provides additional functionality and cybersecurity

Windows 11 operating system compatibility for increased cybersecurity
User configuration and logging feature
Administrators can provide additional access for selected users and functions

Remote access solution for analysis and review

CytoInsight GSL offers the option of remote access for brightfield and fluorescence analysis cases
Access to CytoInsight GSL is also an ideal solution for Director review and labs that need to collaborate across geographical remote sites

Reagents/Consumables

Kreatech FISH Probes

By combining the advanced performance of REPEAT-FREE technology with Kreatech Diagnostics proprietary ULS labeling method, Kreatech probes offer the next generation of FISH probe performance

REPEAT-FREE technology

Kreatech FISH Probes are constructed using the REPEAT-FREE technology that is based on subtractive hybridization, which specifically removes all repetitive elements from the probe that are dispersed throughout the target area of interest. Eliminating these repeat sequences leads to more specific binding kinetics and makes the need for blocking DNA obsolete.

ULS labeling method

Our DNA probes are labeled with Kreatech proprietary ULS™ linkage system leading to a very homogenous and consistent labeling of fluorescent dyes.

See Our FISH Probes Menu

Product Specification

CytoInsight GSL Product Specifications

Specification	Description
GSL 120 Capacity	120-slide batch capacity
GSL 10 Capacity	10-slide batch capacity
Camera Port	Fixed 1x C-mount with no optics
Nominal Input Voltage	120V / 230V AC (auto sensing)
Mains Supply	+/- 10% Rated Voltage
Input Frequency	50 Hz +/- 3 Hz (auto sensing)
Noise Emission	<60 dBA normal operation
Storage Conditions	Temperature: -15° to 45°C (5° to 113°F) Humidity: 20-90% non-condensing (38.7°C)
Operation (General)	Indoor Use Ambient Temperature: 15° to 35°C (59° to 95°F) Humidity: 20-70% non-condensing Maximum relative humidity: 70% for temperatures up to 36ºC (96.8ºF)
Operation (GSL scanning)	Optimal temperature: 20° to 25°C (68° to 77°F).

Configurations

Scanning Station with GSL120 Automated Slide Loader

CytoInsight GSL Workstation: CytoInsight GSL application software and software protection key, computer with Windows OS, monitor, and UPS.
12 megapixel CMOS camera
Leica DM6 B automated microscope with motorized XY stage & automated oiler
Barcode reader
GSL 120 automated slide loader and scanning system capable of accommodating 120 microscope slides

Scanning Station with GSL10 Automated Slide Loader

CytoInsight GSL Workstation: CytoInsight GSL application software and software protection key, computer with Windows OS, monitor, and UPS.
12 megapixel CMOS camera
Leica DM6 B automated microscope with motorized XY stage & automated oiler
Barcode reader
GSL 10 automated slide loader and scanning system capable of accommodating 10 microscope slides

Capture Station with Leica DM6 B Microscope

CytoInsight GSL Workstation: CytoInsight GSL application software and software protection key, computer with Windows OS, monitor, and UPS.
12 megapixel CMOS camera
Leica DM6 B automated microscope with mechanical XY stage
Xylis LED lamp for FISH station

Capture Station (without Microscope)

CytoInsight GSL Workstation: CytoInsight GSL application software and software protection key, computer with Windows OS, monitor, and UPS.
12 megapixel CMOS camera
Xylis LED lamp for FISH station (optional)

Review Station

CytoInsight GSL application software and software protection key
Computer with Windows OS, monitor, and UPS

CytoInsight GSL Product Configuration Comparison

Configuration	Capture Station without Microscope	Capture Station with Microscope	Scanning Station with GSL 10 Automated Slide Loader	Scanning Station with GSL 120 Automated Slide Loader
CytoInsight GSL software application
Software protection key
Computer with Windows OS
Display monitor
Uninterrupted Power Supply (UPS)
12 megapixel CMOS camera
Xylis LED lamp for FISH station	Optional
Leica DM6 B automated microscope
XY stage		Motorized	Motorized	Motorized
Automated oiler
Barcode reader
Automated Slide Loader			GSL 10	GSL 120
Slide loader batch capacity			10 slides	120 slides